Efficacy and Safety of Analgesics and Sedatives during Radiofrequency Catheter Ablation of Atrial Fibrillation: A Network Meta-Analysis

Background: Atrial fibrillation is the most common tachyarrhythmia, while catheter ablation is an effective therapy for atrial fibrillation.However, pain and nervousness may occur during the procedure.Moreover, a consensus has still not Queen Bookcase Headboard been reached on which is the best kind of analgesic and sedative to use in these procedu

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Genes of ancient microtubule-stabilizing proteins traveled through pre-Cambrian Echinoidea to advanced life forms of dry land and ended up in the human genome as the fusion oncogenes-oncoproteins eml1/EML1-abl/ABL, and eml4/EML4-alk/ALK

The genes eml1/4 of the Echinodermata microtubule-stabilizing gene product-like 1/4 proteins EML1/4 of the sea cucumbers (Holothuroidea) traveled through the evolutionary scale up to the human genome.Human cells malignantly transformed by oncogenes abl or alk enlist the protein products EML1/4 for the activation and protection of the gene product o

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